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College Football Expert Picks, Predictions: Week 10

College football expert picks, predictions for Week 10 including Washington at USC, Notre Dame at Clemson, and Oklahoma at Oklahoma State
Nov 5, 2022; South Bend, Indiana, USA; Notre Dame Fighting Irish running back Audric Estime (7) celebrates with fans on the field after defeating the Clemson Tigers at Notre Dame Stadium. Mandatory Credit: Matt Cashore-USA TODAY Sports

Nov 5, 2022; South Bend, Indiana, USA; Notre Dame Fighting Irish running back Audric Estime (7) celebrates with fans on the field after defeating the Clemson Tigers at Notre Dame Stadium. 

College Football Experts Picks Week 10

Pete Fiutak on X | CFN on X
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- Breakdown of every CFP Top 25 pick

Buffalo at Toledo

Line: Toledo -15.5, o/u: 52.5
7:00 ESPN2

Ball State at Bowling Green

Line: Bowling Green -5.5, o/u: 39.5
7:00 ESPN2

TCU at Texas Tech

Line: Texas Tech -3, o/u: 58.5
7:00, FS1

Wake Forest at Duke

Line: Duke -12.5, o/u: 45
7:30 ESPN

South Alabama at Troy

Line: Line: Troy -5.5, o/u: 45.5
7:30, ESPN2

Boston College at Syracuse

Line: Syracuse -2.5, o/u: 51
7:30, ABC

Colorado State at Wyoming

Line: Wyoming -7, o/u: 42
8:00 CBS Sports Network

Ohio State at Rutgers

Line: Ohio State -18.5, o/u: 42.5
12:00, CBS

Kansas State at Texas

Line: Texas -4, o/u: 51
12:00 FOX

Notre Dame at Clemson

Line: Notre Dame -3, o/u: 45
12:00 ABC

UConn at Tennessee

Line: Tennessee -36, o/u: 53
12:00 SEC Network

Missouri at Georgia

Line: Georgia -15.5, o/u: 55.5
3:30 CBS

Florida State at Pitt

Line: Florida State -21.5, o/u: 51
2:00 CW Network

Penn State at Maryland

Line: Penn State -10.5, o/u: 50
3:30 FOX

Oklahoma at Oklahoma State

Line: Oklahoma -6, o/u: 62
3:30, ABC

Virginia Tech at Louisville

Line: Louisville -9.5, o/u: 48.5
3:30 ACC Network

James Madison at Georgia State

Line: James Madison -5.5, o/u: 54.5
3:30 ESPN2

Cal at Oregon

Line: Oregon -24, o/u: 57.5
5:30, Pac-12 Network

Kansas at Iowa State

Line: Iowa State -2.5, o/u: 54
7:00, ESPN

Purdue at Michigan

Line: Michigan -32.5, o/u: 49
7:30 NBC

Washington at USC

Line: Washington -3.5, o/u: 76
7:30, ABC

Oregon State at Colorado

Line: Oregon State -13, o/u: 63
10:00 ESPN

Boise State at Fresno State

Line: Fresno State -3, o/u: 55
10:00 CBS Sports Network

UCLA at Arizona

Line: UCLA -2.5, o/u: 52
10:30, FS1

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